Radiometric dating results

Potassium-40 is the largest contributor to background in glass vials.A maximum volume of 20 m L is fixed due to the dimensions of current photomultiplier tubes (2 inch diameter).However, glass vials can break when falling on the ground, increasing the risk of contamination.

Many plates and vials exist, and the choice of what type of vial or plate to use will depend on factors such as volume, chemical resistance, safety, and performance in combination with the cocktail of choice.No liquid scintillation cocktail is required, as scintillant is already embedded in the walls of the microplate.In assays using scintillation-embedded plates, separation of "positive" and "negative" signal from the radiochemical is achieved by designing the assay in such a way that the radiochemical is associated with the walls or base of the microplate (and therefore able to interact with the scintillant) under given conditions.In addition to standard protocols using vial counters, radiometric assays can also be performed using higher-throughput detectors: The liquid scintillation counting technique can be applied to hundreds of radiometric applications, and each will require a scintillation cocktail.Almost all cocktails will give counting results with any application, but the quality and reproducibility of the data will depend on the choice of the cocktail as well as on the sample composition, volume, temperature, and counting device.

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